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Patients at highest risk include those in the dose-escalation phase, experiencing active gastrointestinal symptoms (nausea, vomiting, bloating), those with known gastroparesis, or those taking concurrent medications that further delay gastric emptying (such as opioids)

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doi: 10.1158/1078-0432.CCR-06-2965 95 NomiyamaTKawanamiTIrieSHamaguchiYTerawakiYMuraseKet al